Cancer Research Products | Cancer Cell Research Resources | Corning

Unlocking the complexities of cancer is an ongoing challenge. Luckily, countless individuals are determined to discover new and better ways to more effectively prevent, fight or even cure cancer.  

Corning supports this important research with reliable lab products that deliver consistent, repeatable results. Matrigel^® matrix for organoid culture, Matrigel matrix, Transwell^® and FluroBlok^® permeable supports, Elplasia^® plates and spheroid microplates are just a few Corning products being used in cutting edge cancer research studies.

Whether your research is focused on tumor formation, angiogenesis or invasion/migration assays, we have the knowledge and experience to simplify product selection, provide technical support, and set your research up for success - right from the start.

Tumorigenesis is a complex process involving cell mutagenesis and the transformation of cells from normal to aberrant proliferative behavior. Tumor cells escape the normal constraints on cell division and then progress through the stages of uncontrolled cell proliferation and tumor formation. All of the cells derived from the parent tumor cells display tumorigenic behavior and contribute to the tumor mass as it grows. Tumor growth and survival is dependent on the process of angiogenesis, which provides the tumor with a vascular network and blood supply that effectively feeds the tumor cells. The resulting tumor may remain within the tissue of origin (referred to as in situ cancer) or spread to other tissues and organs via the process of metastasis (referred to as invasive cancer).

The process of tumorigenesis begins when a normal cell undergoes mutational changes that initiate and promote the transformation to a tumor cell. As tumor cells engage in uncontrolled proliferation, the tumorigenic cell population can form a tumor mass at the site or tissue of origin.

Featured Products:

• Corning Matrigel matrix for in vitro and in vivo tumor formation assays
• Corning Ultra-Low Attachment spheroid microplates for screening applications
• Corning Matrigel matrix for organoid culture ideal for creating 3D organoid models 
• Corning Elplasia plates for screening applications, as well as cancer/tumor biology

Angiogenesis is the process that governs the formation of new blood vessels. Tumor growth and survival is dependent on the angiogenesis process, which provides the tumor with a vascular network and blood supply that effectively feeds the tumor cells and their microenvironment.

Featured Products:

• Corning Matrigel matrix for endothelial cell tube formation assay
• Corning BioCoat™ endothelial cell migration angiogenesis system

Metastasis via Intravasation: During the intravasation process, tumor cells exit the tumor of origin and invade through the basement membrane and vessel walls into nearby lymphatic or blood vessels.
Secondary Tumor Formation via Extravasation: During extravasation, circulating tumor cells exit the lymphatic or blood vessels by invading through vessel walls and basement membrane into a new tissue or organ.
Featured Assays:

• Transwell Permeable Supports for Invasion/Migration
• Corning BioCoat Tumor Invasion Systems
• Corning FluoroBlok Permeable Supports Systems
• HTS Transwell 96-well Permeable Supports
• Corning 96-well Spheroid Microplates